Selected References for Patricia Janak:

Carnicella, S., Ahmadiantehrani, S., He, D.Y., Nielsen, C.K., Bartlett, S.E., Janak, P.H. and Ron, D. "Cabergoline Decreases Alcohol Drinking and Seeking Behaviors Via Glial Cell Line-Derived Neurotrophic Factor." Biol Psychiatry, 2009.

Rewal, M., Jurd, R., Gill, T.M., He, D.Y., Ron, D. and Janak, P.H. "Alpha4-containing GABAA receptors in the nucleus accumbens mediate moderate intake of alcohol." J Neurosci 29(2): 543-9, 2009.

Blaiss, C.A. and Janak, P.H. "The nucleus accumbens core and shell are critical for the expression, but not the consolidation, of Pavlovian conditioned approach." Behav Brain Res, 2008.

Chaudhri, N., Sahuque, L.L., Cone, J.J. and Janak, P.H. "Reinstated ethanol-seeking in rats is modulated by environmental context and requires the nucleus accumbens core." Eur J Neurosci 28(11): 2288-98, 2008.

Bowers, M.S., Hopf, F.W., Chou, J.K., Guillory, A.M., Chang, S.J., Janak, P.H., Bonci, A. and Diamond, I. "Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma." Proc Natl Acad Sci U S A 105(34): 12533-8, 2008.

Chaudhri, N., Sahuque, L.L. and Janak, P.H. "Context-induced relapse of conditioned behavioral responding to ethanol cues in rats." Biol Psychiatry 64(3): 203-10, 2008.

Logrip, M.L., Janak, P.H. and Ron, D. "Dynorphin is a downstream effector of striatal BDNF regulation of ethanol intake." Faseb J 22(7): 2393-404, 2008.

Tye, K.M., Stuber, G.D., de Ridder, B., Bonci, A. and Janak, P.H. "Rapid strengthening of thalamo-amygdala synapses mediates cue-reward learning." Nature 453(7199): 1253-7, 2008.

Carnicella, S., Kharazia, V., Jeanblanc, J., Janak, P.H. and Ron, D. "GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse." Proc Natl Acad Sci U S A 105(23): 8114-9, 2008.

Bowers, M.S., Chen, B.T., Chou, J.K., Osborne, M.P., Gass, J.T., See, R.E., Bonci, A., Janak, P.H. and Olive, M.F. "Acamprosate attenuates cocaine- and cue-induced reinstatement of cocaine-seeking behavior in rats." Psychopharmacology (Berl) 195(3): 397-406, 2007.

Corbit, L.H. and Janak, P.H. "Inactivation of the lateral but not medial dorsal striatum eliminates the excitatory impact of Pavlovian stimuli on instrumental responding." J Neurosci 27(51): 13977-81, 2007.

Corbit, L.H., Janak, P.H. and Balleine, B.W. "General and outcome-specific forms of Pavlovian-instrumental transfer: the effect of shifts in motivational state and inactivation of the ventral tegmental area." Eur J Neurosci 26(11): 3141-9. Dec, 2007.

Lasek, A.W., Janak, P.H., He, L., Whistler, J.L. and Heberlein, U. "Downregulation of mu opioid receptor by RNA interference in the ventral tegmental area reduces ethanol consumption in mice." Genes Brain Behav 6(8): 728-35. Nov, 2007.

Blaiss, C.A. and Janak, P.H. "Post-training, but not post-reactivation, administration of amphetamine and anisomycin modulates Pavlovian conditioned approach." Neurobiol Learn Mem 87(4): 644-58. May, 2007.

Corbit, L.H. and Janak, P.H. "Ethanol-associated cues produce general pavlovian-instrumental transfer." Alcohol Clin Exp Res 31(5): 766-74. May, 2007.

Tye, K.M. and Janak, P.H. "Amygdala neurons differentially encode motivation and reinforcement." J Neurosci 27(15): 3937-45. Apr 11, 2007.

Wang, J., Carnicella, S., Phamluong, K., Jeanblanc, J., Ronesi, J.A., Chaudhri, N., Janak, P.H., Lovinger, D.M. and Ron, D. "Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum: implications for alcohol drinking behavior." J Neurosci 27(13): 3593-602. Mar 28, 2007.

Zhang, J., Pho, V., Bonasera, S.J., Holtzman, J., Tang, A.T., Hellmuth, J., Tang, S., Janak, P.H., Tecott, L.H. and Huang, E.J. "Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons." Nat Neurosci 10(1): 77-86. Jan, 2007.

Burattini, C., Gill, T.M., Aicardi, G. and Janak, P.H. "The ethanol self-administration context as a reinstatement cue: acute effects of naltrexone." Neuroscience 139(3): 877-87, 2006.

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Blaiss, C.A. and Janak, P.H. "Post-training and post-reactivation administration of amphetamine enhances morphine conditioned place preference." Behav Brain Res 171(2): 329-37, 2006.

Zironi, I., Burattini, C., Aicardi, G. and Janak, P.H. "Context is a trigger for relapse to alcohol." Behav Brain Res 167(1): 150-5, 2006.

Janak, P.H., Wolf, F.W., Heberlein, U., Pandey, S.C., Logrip, M.L. and Ron, D. "BIG news in alcohol addiction: new findings on growth factor pathways BDNF, insulin, and GDNF." Alcohol Clin Exp Res 30(2): 214-21, 2006

Tsiang, M.T. and Janak, P.H. "Alcohol seeking in C57BL/6 mice induced by conditioned cues and contexts in the extinction-reinstatement model." Alcohol 38(2): 81-8, 2006.

Jeanblanc, J., He, D.Y., McGough, N.N., Logrip, M.L., Phamluong, K., Janak, P.H. and Ron, D. "The dopamine D3 receptor is part of a homeostatic pathway regulating ethanol consumption." J Neurosci 26(5): 1457-64, 2006.

Ron, D. and Janak, P.H. "GDNF and addiction." Rev Neurosci 16(4): 277-85, 2005.

He, D.Y., McGough, N.N., Ravindranathan, A., Jeanblanc, J., Logrip, M.L., Phamluong, K., Janak, P.H. and Ron, D. "Glial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption." J Neurosci 25(3): 619-28, 2005.

McGough, N.N., He, D.Y., Logrip, M.L., Jeanblanc, J., Phamluong, K., Luong, K., Kharazia, V., Janak, P.H. and Ron, D. "RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction." J Neurosci 24(46): 10542-52, 2004.

Janak, P.H., Chen, M.T. and Caulder, T. "Dynamics of neural coding in the accumbens during extinction and reinstatement of rewarded behavior." Behav Brain Res 154(1): 125-35, 2004.

Arolfo, M.P., Yao, L., Gordon, A.S., Diamond, I. and Janak, P.H. "Ethanol operant self-administration in rats is regulated by adenosine A2 receptors." Alcohol Clin Exp Res 28(9): 1308-16, 2004.

Nie, H. and Janak, P.H. "Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats." Psychopharmacology (Berl) 168(1-2): 222-8, 2003.

Janak, P.H. and Michael Gill, T. "Comparison of the effects of allopregnanolone with direct GABAergic agonists on ethanol self-administration with and without concurrently available sucrose." Alcohol 30(1): 1-7, 2003.

Yao, L., Arolfo, M.P., Dohrman, D.P., Jiang, Z., Fan, P., Fuchs, S., Janak, P.H., Gordon, A.S. and Diamond, I. "betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption." Cell 109(6): 733-43, 2002.

Chen, M.T., Morales, M., Woodward, D.J., Hoffer, B.J. and Janak, P.H. "In vivo extracellular recording of striatal neurons in the awake rat following unilateral 6-hydroxydopamine lesions." Exp Neurol 171(1): 72-83, 2001.

Chang, J.Y., Janak, P.H. and Woodward, D.J. "Neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats." Neuroscience 99(3): 433-43, 2000.

Janak, P.H., Chang, J.Y. and Woodward, D.J. "Neuronal spike activity in the nucleus accumbens of behaving rats during ethanol self-administration." Brain Res 817(1-2): 172-84, 1999.

Janak, P.H., Redfern, J.E. and Samson, H.H. "The reinforcing effects of ethanol are altered by the endogenous neurosteroid, allopregnanolone." Alcohol Clin Exp Res 22(5): 1106-12, 1998.