Home Publications Publications 2002-2005
Publications 2002-2005
2005

Albarran, B., L. Goncalves, S. Salmen, L. Borges,  H. Fields, A. Soyano, H. Montes and L. Berrueta. "Profiles of NK, NKT cell activation and cytokine production following vaccination against hepatitis B." Apmis 113(7-8): 526-35. 
Bainton, R. J., L. T. Tsai, T. Schwabe, M. DeSalvo, U.  Gaul and  U. Heberlein. "moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in  Drosophila." Cell 123(1): 145-56. 

Bartlett, S. E., J. Enquist, F. W. Hopf, J. H. Lee, F. Gladher, V. Kharazia, M. Waldhoer, W. S. Mailliard, R. Armstrong,  A. Bonci and  J. L. Whistler. "Dopamine responsiveness is regulated by targeted sorting of D2 receptors." Proc Natl Acad Sci U S A 102(32): 11521-6. 
Boettiger, C. A. and M. D'Esposito. "Frontal networks for learning and executing arbitrary stimulus-response associations." J Neurosci 25(10): 2723-32. 

Bonci, A. and F. W. Hopf. "The dopamine D2 receptor: new surprises from an old friend." Neuron 47(3): 335-8.

Bonci, A. and W. A. Carlezon, Jr. "Ion channels and intracellular signaling proteins as potential targets for novel therapeutics for addictive and depressive disorders." Pharmacol Ther 108(1): 65-75. 

Carnell, L., J. Illi, S. W. Hong and  S. L. McIntire. "The G-protein-coupled serotonin receptor SER-1 regulates egg laying and male mating behaviors in  Caenorhabditis elegans." J Neurosci 25(46): 10671-81.

Chen, Y., A. R. Cantrell,  R. O. Messing, T. Scheuer and W. A. Catterall. "Specific modulation of Na+ channels in hippocampal neurons by protein kinase C epsilon." J Neurosci 25(2): 507-13. 

Chou, W. H. and  R. O. Messing. "Protein kinase C isozymes in stroke." Trends Cardiovasc Med 15(2): 47-51.

Corl, A. B., A. R. Rodan and  U. Heberlein. "Insulin signaling in the nervous system regulates ethanol intoxication in  Drosophila melanogaster." Nat Neurosci 8(1): 18-9. 

Dworkin, R. H. and  H. L. Fields. "Fibromyalgia from the perspective of neuropathic pain." J Rheumatol Suppl 75: 1-5.

He, D. Y., N. N. McGough, A. Ravindranathan, J. Jeanblanc, M. L. Logrip, K. Phamluong,  P. H. Janak and  D. Ron. "Glial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption." J Neurosci 25(3): 619-28. 

He, L. and  J. L. Whistler. "An opiate cocktail that reduces morphine tolerance and dependence." Curr Biol 15(11): 1028-33.

Hoffman, G. A., A. Harrington and  H. L. Fields. "Pain and the placebo: What we have learned." Perspect Biol Med 48(2): 248-65. 

Hopf, F. W., W. S. Mailliard, G. F. Gonzalez,  I. Diamond and  A. Bonci. "Atypical protein kinase C is a novel mediator of dopamine-enhanced firing in nucleus accumbens neurons." J Neurosci 25(4): 985-9. 

Jones, S. and  A. Bonci. "Synaptic plasticity and drug addiction." Curr Opin Pharmacol 5(1): 20-5. 

Kerns, R. T., A. Ravindranathan, S. Hassan, M. P. Cage, T. York, J. M. Sikela, R. W. Williams and  M. F. Miles. "Ethanol-responsive brain region expression networks: Implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice." J Neurosci 25(9): 2255-66.

Kostenis, E., L. Martini, J. Ellis, M. Waldhoer, A. Heydorn, M. M. Rosenkilde, P. K. Norregaard, R. Jorgensen,  J. L. Whistler and G. Milligan. "A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity." J Pharmacol Exp Ther 313(1): 78-87. 

Littler, C. M., C. A. Wehling, K. A. Fagan,  R. O. Messing and E. C. Dempsey. "Divergent contractile and structural responses of the murine protein kinase C-epsilon null pulmonary circulation to chronic hypoxia." Chest 128(6 Suppl): 620S-621S.

Margolis, E. B., G. O. Hjelmstad,  A. Bonci and  H. L. Fields. "Both kappa and mu opioid agonists inhibit glutamatergic input to ventral tegmental area neurons." J Neurophysiol 93(6): 3086-93. 

Meng,  I.  D., J. P. Johansen,  I. Harasawa and  H. L. Fields. "Kappa opioids inhibit physiologically identified medullary pain modulating neurons and reduce morphine antinociception." J Neurophysiol 93(3): 1138-44.

Mitchell, J. M.,  H. L. Fields, M. D'Esposito and C. A. Boettiger. "Impulsive responding in alcoholics." Alcohol Clin Exp Res 29(12): 2158-69. 

Mitchell, J. M., M. T. Liang and  H. L. Fields. "A single injection of the kappa opioid antagonist norbinaltorphimine increases ethanol consumption in rats." Psychopharmacology (Berl) 182(3): 384-92.

Newton, P. M., K. Tully, T. McMahon, J. Connolly, J. Dadgar, S. N. Treistman and  R. O. Messing. "Chronic ethanol exposure induces an N-type calcium channel splice variant with altered channel kinetics." FEBS Lett 579(3): 671-6. 

Nicola, S. M., S. A. Taha, S. W. Kim and  H. L. Fields. "Nucleus accumbens dopamine release is necessary and sufficient to promote the behavioral response to reward-predictive cues." Neuroscience 135(4): 1025-33.

Olive, M. F., A. J. McGeehan, J. R. Kinder, T. McMahon,  C. W. Hodge,  P. H. Janak and  R. O. Messing. "The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism." Mol Pharmacol 67(2): 349-55. 

Purdy, R. H., C. F. Valenzuela,  P. H. Janak, D. A. Finn, G. Biggio and T. Backstrom. "Neuroactive steroids and ethanol." Alcohol Clin Exp Res 29(7): 1292-8.

Ron, D. and  P. H. Janak. "GDNF and addiction." Rev Neurosci 16(4): 277-85. 

Ron, D. and R. Jurd. "The "ups and downs" of signaling cascades in addiction." Sci STKE 2005(309): re14. 

Rowbotham, M. C., L. A. Reisner, P. S. Davies and  H. L. Fields. "Treatment response in antidepressant-naive postherpetic neuralgia patients: double-blind, randomized trial." J Pain 6(11): 741-6.

Scholz, H., M. Franz and  U. Heberlein. "The hangover gene defines a stress pathway required for ethanol tolerance development." Nature 436(7052): 845-7. 

Song, M. and  R. O. Messing. "Protein kinase C regulation of GABAA receptors." Cell Mol Life Sci 62(2): 119-27.

Suvarna, N., S. L. Borgland, J. Wang, K. Phamluong, Y. P. Auberson,  A. Bonci and  D. Ron. "Ethanol alters trafficking and functional N-methyl-D-aspartate receptor NR2 subunit ratio via H-Ras." J Biol Chem 280(36): 31450-9. 

Taha, S. A. and  H. L. Fields. "Encoding of palatability and appetitive behaviors by distinct neuronal populations in the nucleus accumbens." J Neurosci 25(5): 1193-202.

Thibault, C., S. Hassan and  M. Miles. "Using  in vitro models for expression profiling studies on ethanol and drugs of abuse." Addict Biol 10(1): 53-62. 

Waldhoer, M., J. Fong, R. M. Jones, M. M. Lunzer, S. K. Sharma, E. Kostenis, P. S. Portoghese and  J. L. Whistler. "A heterodimer-selective agonist shows  in vivo relevance of G protein-coupled receptor dimers." Proc Natl Acad Sci U S A 102(25): 9050-5.

Xuan, Y. T., Y. Guo, Y. Zhu, O. L. Wang, G. Rokosh,  R. O. Messing and R. Bolli. "Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning." Circulation 112(13): 1971-8. 

Yao, L., K. McFarland, P. Fan, Z. Jiang, Y. Inoue and  I. Diamond. "Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior." Proc Natl Acad Sci U S A 102(24): 8746-51. 

2004

Appel, S. B., W. J. McBride, M. Diana,  I. Diamond, A. Bonci and M. S. Brodie. "Ethanol effects on dopaminergic "reward" neurons in the ventral tegmental area and the mesolimbic pathway." Alcoholism:   Clinical and Experimental Research 28: 1768-1778.

Arolfo, M. P., L. Yao,  A. S. Gordon,  I. Diamond and  P. H. Janak. "Ethanol operant self-administration in rats is regulated by adenosine A2 receptors." Alcohol Clin Exp Res 28(9): 1308-1316. 

Berger, K. H.,  U. Heberlein and M. S. Moore. "Rapid and chronic: two distinct forms of ethanol tolerance in  Drosophila." Alcohol Clin Exp Res 28(10): 1469-80.

Bettinger, J. C. and  S. L. McIntire. "State-dependency in  C. elegans." Genes Brain Behav 3(5): 266-72. 

Bettinger, J. C., L. Carnell, A. G. Davies and  S. L. McIntire. "The use of  Caenorhabditis elegans in molecular neuropharmacology." Int Rev Neurobiol 62: 195-212.

Borgland, S. L., R. C. Malenka and  A. Bonci. "Acute and chronic cocaine-induced potentiation of synaptic strength in the ventral tegmental area: Electrophysiological and behavioral correlates in individual rats." J Neurosci 24(34): 7482-90. 

Chandler, L. J.,  A. Bonci, G. S. Wand and R. A. Morrisett. "Recent advances in cyclic-adenosine monophosphate/protein kinase A signaling in ethanol-induced synaptic and behavioral alterations." Alcohol Clin Exp Res 28(7): 1129-1136.

Cho, W.,  U. Heberlein and F. W. Wolf. "Habituation of an odorant-induced startle response in  Drosophila." Genes Brain Behav 3(3): 127-37. 

Choi, D. S., M. G. Cascini, W. Mailliard, H. Young, P. Paredes, T. McMahon,  I. Diamond,  A. Bonci and  R. O. Messing. "The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference." Nat Neurosci 7(8): 855-61.

Chou, W. H., D. S. Choi, H. Zhang, D. Mu, T. McMahon, V. N. Kharazia, C. A. Lowell, D. M. Ferriero and  R. O. Messing. "Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury." J Clin Invest 114(1): 49-56. 

Constantinescu, A., M. Wu, O. Asher and  I. Diamond. "cAMP-dependent protein kinase type I regulates ethanol-induced cAMP response element-mediated gene expression via activation of CREB-binding protein and inhibition of MAPK." J Biol Chem 279(41): 43321-9.

Davies, A. G. and  S. L. McIntire. "Using  C. elegans to screen for targets of ethanol and behavior-altering drugs." Biol Proced Online 6: 113-119. 

Davies, A. G., J. C. Bettinger, T. R. Thiele, M. E. Judy and  S. L. McIntire. "Natural variation in the npr-1 gene modifies ethanol responses of wild strains of  C. elegans." Neuron 42(5): 731-43.

Dong, Y., D. Saal, M. Thomas, R. Faust,  A. Bonci, T. Robinson and R. C. Malenka. "Cocaine-induced potentiation of synaptic strength in dopamine neurons: behavioral correlates in GluRA(-/-) mice." Proc Natl Acad Sci U S A 101(39): 14282-7. 

Fields, H. "State-dependent opioid control of pain." Nat Rev Neurosci 5(7): 565-75.

Gray, M. O., H. Z. Zhou,  I. Schafhalter-Zoppoth, P. Zhu, D. Mochly-Rosen and  R. O. Messing. "Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon." J Biol Chem 279(5): 3596-604. 

Heydorn, A., B. P. Sondergaard, B. Ersboll, B. Holst, F. C. Nielsen, C. R. Haft,  J. Whistler and T. W. Schwartz. "A library of 7TM receptor C-terminal tails: Interactions with the proposed post-endocytic sorting proteins EBP50, NSF, SNX1 and GASP." J Biol Chem 279(52): 54291-303.

Hjelmstad, G. O. "Dopamine excites nucleus accumbens neurons through the differential modulation of glutamate and GABA release." J Neurosci 24(39): 8621-8. 

Hsu, L. C., R. M. Lee and  R. L. White. "The HPV16 E6/E7 oncogene sensitizes human ovarian surface epithelial cells to low-dose but not high-dose 5-FU and 5-FUdR." Biochem Biophys Res Commun 320(1): 249-55.

Janak, P. H., M. T. Chen and T. Caulder. "Dynamics of neural coding in the accumbens during extinction and reinstatement of rewarded behavior." Behav Brain Res 154(1): 125-35. 

Johansen, J. P. and  H. L. Fields. "Glutamatergic activation of anterior cingulate cortex produces an aversive teaching signal." Nat Neurosci 7(4): 398-403.

Kim, H., M. J. Rogers, J. E. Richmond and  S. L. McIntire. "SNF-6 is an acetylcholine transporter interacting with the dystrophin complex in  Caenorhabditis elegans." Nature 430(7002): 891-6. 

Kim, J. A., K. A. Pollak, G. O. Hjelmstad and  H. L. Fields. "A single cocaine exposure enhances both opioid reward and aversion through a ventral tegmental area-dependent mechanism." Proc Natl Acad Sci U S A 101(15): 5664-9.

Koenig, H. N. and M. F. Olive. "The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions." Psychoneuroendocrinology 29(8): 999-1003. 

Liu, J., J. Stevens, N. Matsunami and  R. L. White. "Targeted degradation of beta-catenin by chimeric F-box fusion proteins." Biochem Biophys Res Commun 313(4): 1023-9.

Mailliard, W. S. and  I. Diamond. "Recent advances in the neurobiology of alcoholism: the role of adenosine." Pharmacol Ther 101(1): 39-46. 

May, S. R., N. J. Stewart, W. Chang and  A. S. Peterson. "A Titin mutation defines roles for circulation in endothelial morphogenesis." Dev Biol 270(1): 31-46.

McGeehan, A. J.,  P. H. Janak and M. F. Olive. "Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, d-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice." Psychopharmacology (Berl) 174: 266-273. 

McGough, N. N., D. Y. He, M. L. Logrip, J. Jeanblanc, K. Phamluong, K. Luong, V. Kharazia,  P. H. Janak and  D. Ron. "RACK1 and brain-derived neurotrophic factor: A homeostatic pathway that regulates alcohol addiction." J Neurosci 24(46): 10542-52.

Neilson, D. E., H. S. Feiler,  K. C. Wilhelmsen, A. Lynn, R. M. Eiben, D. S. Kerr and M. L. Warman. "Autosomal dominant acute necrotizing encephalopathy maps to 2q12.1-2q13." Ann Neurol 55(2): 291-4. 

Newton, P. M., C. J. Orr, M. J. Wallace, C. Kim, H. S. Shin and  R. O. Messing. "Deletion of N-type calcium channels alters ethanol reward and reduces ethanol consumption in mice." J Neurosci 24(44): 9862-9.

Nicola, S. M., F. Woodward Hopf and G. O. Hjelmstad. "Contrast enhancement: a physiological effect of striatal dopamine?" Cell Tissue Res 318(1): 93-106. 

Nicola, S. M.,  I. A. Yun, K. T. Wakabayashi and  H. L. Fields. "Cue-evoked firing of nucleus accumbens neurons encodes motivational significance during a discriminative stimulus task." J Neurophysiol 91(4): 1840-65.

Nicola, S. M.,  I. A. Yun, K. T. Wakabayashi and  H. L. Fields. "Firing of nucleus accumbens neurons during the consummatory phase of a discriminative stimulus task depends on previous reward predictive cues." J Neurophysiol 91(4): 1866-82. 

Olive, M. F. and  R. O. Messing. "Protein kinase C isozymes and addiction." Mol Neurobiol 29(2): 139-54.

Olive, M. F., A. J. McGeehan, J. R. Kinder, T. McMahon,  C. W. Hodge,  P. H. Janak and  R. O. Messing. "The mGluR5 antagonist MPEP decreases ethanol consumption via a PKC{epsilon}-dependent mechanism." Mol Pharmacol 67: 349-355. 

Papanastassiou, A. M.,  H. L. Fields and  I.  D. Meng. "Local application of the cannabinoid receptor agonist, WIN 55,212-2, to spinal trigeminal nucleus caudalis differentially affects nociceptive and non-nociceptive neurons." Pain 107(3): 267-75.

Ron, D. "Signaling cascades regulating NMDA receptor sensitivity to ethanol." Neuroscientist 10(4): 325-36. 

Seaton, K. L., J. L. Cornell,  K. C. Wilhelmsen and C. Vieten. "Effective strategies for recruiting families ascertained through alcoholic probands." Alcohol Clin Exp Res 28(1): 78-84.

Souroujon, M. C., L. Yao, H. Chen, G. Endemann, H. Khaner, V. Geeraert, D. Schechtman,  A. S. Gordon,  I. Diamond and D. Mochly-Rosen. "State-specific monoclonal antibodies identify an intermediate state in epsilon protein kinase C activation." J Biol Chem 279(17): 17617-24. 

Thornton, C., K. C. Tang, K. Phamluong, K. Luong, A. Vagts, D. Nikanjam, R. Yaka and  D. Ron. "Spatial and temporal regulation of RACK1 function and N-methyl-D-aspartate receptor activity through WD40 motif-mediated dimerization." J Biol Chem 279(30): 31357-64.

Tsai, L. T., R. J. Bainton, J. Blau and  U. Heberlein. "Lmo mutants reveal a novel role for circadian pacemaker neurons in cocaine-induced behaviors." PLoS Biol 2(12): e408. 

Vieten, C., K. L. Seaton, H. S. Feiler and  K. C. Wilhelmsen. "The  University of  California,  San Francisco Family Alcoholism Study. I. Design, methods, and demographics." Alcohol Clin Exp Res 28(10): 1509-16.

Wakabayashi, K. T.,  H. L. Fields and S. M. Nicola. "Dissociation of the role of nucleus accumbens dopamine in responding to reward-predictive cues and waiting for reward." Behav Brain Res 154(1): 19-30. 

Waldhoer, M., S. E. Bartlett and  J. L. Whistler. "Opioid receptors." Annu Rev Biochem 73: 953-90. 
Wilhelmsen, K. C., M. S. Forman, H. J. Rosen, L. I. Alving, J. Goldman, J. Feiger, J. V. Lee, S. K. Segall, J. H. Kramer, C. Lomen-Hoerth, K. P. Rankin, J. Johnson, H. S. Feiler, M. W. Weiner, V. M. Lee, J. Q. Trojanowski and B. L. Miller. "17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions." Arch Neurol 61(3): 398-406. 

Yun,  I. A., K. T. Wakabayashi,  H. L. Fields and S. M. Nicola. "The ventral tegmental area is required for the behavioral and nucleus accumbens neuronal firing responses to incentive cues." J Neurosci 24(12): 2923-33.

Yun,  I. A., S. M. Nicola and  H. L. Fields. "Contrasting effects of dopamine and glutamate receptor antagonist injection in the nucleus accumbens suggest a neural mechanism underlying cue-evoked goal-directed behavior." Eur J Neurosci 20(1): 249-63. 

Zarbalis, K., S. R. May, Y. Shen, M. Ekker, J. L. Rubenstein and  A. S. Peterson. "A focused and efficient genetic screening strategy in the mouse: Identification of mutations that disrupt cortical development." PLoS Biol 2(8): E219.

Zoltewicz, J. S., N. J. Stewart, R. Leung and  A. S. Peterson. "Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis." Development 131(1): 3-14. 

2003

Bie, B.,  H. L. Fields, J. T. Williams and Z. Z. Pan. "Roles of alpha1- and alpha2-adrenoceptors in the nucleus raphe magnus in opioid analgesia and opioid abstinence-induced hyperalgesia." J Neurosci 23(21): 7950-7. 

Bonci, A., G. Bernardi, P. Grillner and N. B. Mercuri. "The dopamine-containing neuron: Maestro or simple musician in the orchestra of addiction?" Trends Pharmacol Sci 24(4): 172-7.

Choi, D. S., H. Young, T. McMahon, D. Wang and  R. O. Messing. "The mouse RACK1 gene is regulated by nuclear factor-kappa B and contributes to cell survival." Mol Pharmacol 64(6): 1541-8. 

Davies, A. G., J. T. Pierce-Shimomura, H. Kim, M. K. VanHoven, T. R. Thiele,  A. Bonci, C. I. Bargmann and  S. L. McIntire. "A central role of the BK potassium channel in behavioral responses to ethanol in  C. elegans." Cell 115(6): 655-66.

Hjelmstad, G. O. and  H. L. Fields. "Kappa opioid receptor activation in the nucleus accumbens inhibits glutamate and GABA release through different mechanisms." J Neurophysiol 89(5): 2389-2395. 

Hopf, F. W., M. G. Cascini,  A. S. Gordon,  I. Diamond and  A. Bonci. "Cooperative activation of dopamine D1 and D2 receptors increases spike firing of nucleus accumbens neurons via G-protein betagamma subunits." J Neurosci 23(12): 5079-87.

Janak, P. H. and T. Michael Gill. "Comparison of the effects of allopregnanolone with direct GABAergic agonists on ethanol self-administration with and without concurrently available sucrose." Alcohol 30(1): 1-7. 

Knox, B. E., E. Salcedo, K. Mathiesz, J. Schaefer, W. H. Chou, L. V. Chadwell, W. C. Smith, S. G. Britt and R. B. Barlow. "Heterologous expression of limulus rhodopsin." J Biol Chem 278(42): 40493-502.

Littler, C. M., K. G. Morris, Jr., K. A. Fagan, I. F. McMurtry,  R. O. Messing and E. C. Dempsey. "Protein kinase C-epsilon-null mice have decreased hypoxic pulmonary vasoconstriction." Am J Physiol Heart Circ Physiol 284(4): H1321-31. 

Margolis, E. B., G. O. Hjelmstad,  A. Bonci and  H. L. Fields. "Kappa-opioid agonists directly inhibit midbrain dopaminergic neurons." J Neurosci 23(31): 9981-6.

McGeehan, A. J. and M. F. Olive. "The anti-relapse compound acamprosate inhibits the development of a conditioned place preference to ethanol and cocaine but not morphine." Br J Pharmacol 138(1): 9-12. 

Miyamae, M., N. Domae, H. Z. Zhou, S. Shingo,  I. Diamond and V. M. Figueredo. "Phospholipase C activation is required for cardioprotection by ethanol consumption." Exp Clin Cardiol 8(4): 184-188.

Nie, H. and  P. H. Janak. "Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats." Psychopharmacology (Berl) 168: 222-228. 

Olive, M. F., K. K. Mehmert, H. N. Koenig, R. Camarini, J. A. Kim, M. A. Nannini, C. J. Ou and  C. W. Hodge. "A role for corticotropin releasing factor (CRF) in ethanol consumption, sensitivity, and reward as revealed by CRF-deficient mice." Psychopharmacology (Berl) 165(2): 181-7.

Potrebic, S., A. H. Ahn, K. Skinner,  H. L. Fields and A. I. Basbaum. "Peptidergic nociceptors of both trigeminal and dorsal root ganglia express serotonin 1D receptors: implications for the selective antimigraine action of triptans." J Neurosci 23(34): 10988-97. 

Proctor, W. R., W. Poelchen, B. J. Bowers, J. M. Wehner,  R. O. Messing and T. V. Dunwiddie. "Ethanol differentially enhances hippocampal GABA A receptor-mediated responses in protein kinase C gamma (PKC gamma) and PKC epsilon null mice." J Pharmacol Exp Ther 305(1): 264-70.

Saal, D., Y. Dong,  A. Bonci and R. C. Malenka. "Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons." Neuron 37(4): 577-82. 

Schuckit, M. A., J. R. Kelsoe, D. L. Braff and  K. C. Wilhelmsen. "Some possible genetic parallels across alcoholism, bipolar disorder and schizophrenia." J Stud Alcohol 64(2): 157-9.

Siegel, D. H., G. H. Ashton, H. G. Penagos, J. V. Lee, H. S. Feiler,  K. C. Wilhelmsen, A. P. South, F. J. Smith, A. R. Prescott, V. Wessagowit, N. Oyama, M. Akiyama, D. Al Aboud, K. Al Aboud, A. Al Githami, K. Al Hawsawi, A. Al Ismaily, R. Al-Suwaid, D. J. Atherton, R. Caputo, J. D. Fine, I. J. Frieden, E. Fuchs, R. M. Haber, T. Harada, Y. Kitajima, S. B. Mallory, H. Ogawa, S. Sahin, H. Shimizu, Y. Suga, G. Tadini, K. Tsuchiya, C. B. Wiebe, F. Wojnarowska, A. B. Zaghloul, T. Hamada, R. Mallipeddi, R. A. Eady, W. H. McLean, J. A. McGrath and E. H. Epstein. "Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome." Am J Hum Genet 73(1): 174-87. 

Sobrido, M. J., B. L. Miller, N. Havlioglu, V. Zhukareva, Z. Jiang, Z. S. Nasreddine, V. M. Lee, T. W. Chow,  K. C. Wilhelmsen, J. L. Cummings, J. Y. Wu and D. H. Geschwind. "Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia." Arch Neurol 60(5): 698-702.

Swan, G. E., K. S. Hudmon, L. M. Jack, K. Hemberger, D. Carmelli, T. V. Khroyan, H. Z. Ring, H. Hops, J. A. Andrews, E. Tildesley, D. McBride, N. Benowitz, C. Webster,  K. C. Wilhelmsen, H. S. Feiler, B. Koenig, L. Caron, J. Illes and L. S. Cheng. "Environmental and genetic determinants of tobacco use: methodology for a multidisciplinary, longitudinal family-based investigation." Cancer Epidemiol Biomarkers Prev 12(10): 994-1005. 

Thornton, C., R. Yaka, S. Dinh and  D. Ron. "H-Ras modulates N-Methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity." J Biol Chem 278(26): 23823-23829.

Ungless, M. A., V. Singh, T. L. Crowder, R. Yaka,  D. Ron and  A. Bonci. "Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons." Neuron 39(3): 401-7. 

Vagts, A. J., D. Y. He, R. Yaka and  D. Ron. "Cellular adaptation to chronic ethanol results in altered compartmentalization and function of the scaffolding protein RACK1." Alcohol Clin Exp Res 27(10): 1599-605.

Waldhoer, M., P. Casarosa, M. M. Rosenkilde, M. J. Smit, R. Leurs,  J. L. Whistler and T. W. Schwartz. "The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis." J Biol Chem 278(21): 19473-82. 

Wilhelmsen, K. C., M. Schuckit, T. L. Smith, J. V. Lee, S. K. Segall, H. S. Feiler and J. Kalmijn. "The search for genes related to a low-level response to alcohol determined by alcohol challenges." Alcohol Clin Exp Res 27(7): 1041-7.

Yaka, R., D. Y. He, K. Phamluong and  D. Ron. "Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-Methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1." J Biol Chem 278(11): 9630-8. 

Yaka, R., K. C. Tang, R. Camarini,  P. H. Janak and  D. Ron. "Fyn kinase and NR2B-containing NMDA receptors regulate acute ethanol sensitivity but not ethanol intake or conditioned reward." Alcohol Clin Exp Res 27(11): 1736-42.

Yaka, R., K. Phamluong and  D. Ron. "Scaffolding of  Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol." J Neurosci 23(9): 3623-32. 

Yao, L., P. Fan, Z. Jiang, W. S. Mailliard,  A. S. Gordon and  I. Diamond. "Addicting drugs utilize a synergistic molecular mechanism in common requiring adenosine and Gi-beta gamma dimers." Proc Natl Acad Sci U S A 100(24): 14379-84.

Yun,  I. A. and  H. L. Fields. "Basolateral amygdala lesions impair both cue- and cocaine-induced reinstatement in animals trained on a discriminative stimulus task." Neuroscience 121(3): 747-57. 

2002

Alvarez, V. A., S. Arttamangkul, V. Dang, A. Salem,  J. L. Whistler, M. Von Zastrow, D. K. Grandy and J. T. Williams. "mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization." J Neurosci 22(13): 5769-76. 

Asher, O., T. D. Cunningham, L. Yao,  A. S. Gordon and  I. Diamond. "Ethanol stimulates cAMP-responsive element (CRE)-mediated transcription via CRE-binding protein and cAMP-dependent protein kinase." J Pharmacol Exp Ther 301(1): 66-70.

Bartlett, S. E. and  J. L. Whistler. "The near death experience of delta opioid receptors leads to new drug targets." Molecular Interventions 2(3): 1134-136. 

Chanut, F., K. Woo,  S. Pereira, T. J. Donohoe, S. Y. Chang, T. R. Laverty, A. P. Jarman and  U. Heberlein. "Rough eye is a gain-of-function allele of amos that disrupts regulation of the proneural gene atonal during  Drosophila retinal differentiation." Genetics 160(2): 623-35.

Choi, D. S., D. Wang, J. Dadgar, W. S. Chang and  R. O. Messing. "Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice." J Neurosci 22(22): 9905-11. 

Constantinescu, A.,  A. S. Gordon and  I. Diamond. "cAMP-dependent protein kinase types I and II differentially regulate cAMP response element-mediated gene expression: Implications for neuronal responses to ethanol." J Biol Chem 277(21): 18810-6.

Dohrman, D. P., H. M. Chen,  A. S. Gordon and  I. Diamond. "Ethanol-induced translocation of protein kinase A occurs in two phases: Control by different molecular mechanisms." Alcohol Clin Exp Res 26(3): 407-15. 

Fujiwara, M., P. Sengupta and  S. L. McIntire. "Regulation of body size and behavioral state of  C. elegans by sensory perception and the EGL-4 cGMP-dependent protein kinase." Neuron 36(6): 1091-102.

He, D. Y., A. J. Vagts, R. Yaka and  D. Ron. "Ethanol induces gene expression via nuclear compartmentalization of receptor for activated C kinase 1." Mol Pharmacol 62(2): 272-80. 

He, L., J. Fong, M. von Zastrow and  J. L. Whistler. "Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization." Cell 108(2): 271-82.

Hodge, C. W., J. Raber, T. McMahon, H. Walter, A. M. Sanchez-Perez, M. F. Olive, K. Mehmert, A. L. Morrow and  R. O. Messing. "Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon." J Clin Invest 110(7): 1003-10. 

Jin, Z. Q., H. Z. Zhou, P. Zhu, N. Honbo, D. Mochly-Rosen,  R. O. Messing, E. J. Goetzl, J. S. Karliner and M. O. Gray. "Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts." Am J Physiol Heart Circ Physiol 282(6): H1970-7.

Koenig, H. N. and M. F. Olive. "Ethanol consumption patterns and conditioned place preference in mice lacking preproenkephalin." Neurosci Lett 325(2): 75-8. 

Melis, M., R. Camarini, M. A. Ungless and  A. Bonci. "Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single  in vivo ethanol exposure."  J Neurosci 22(6): 2074-82.

Nadal, R., A. Armario and  P. H. Janak.  "Positive relationship between activity in a novel environment and operant ethanol self-administration in rats." Psychopharmacology (Berl) 162(3): 333-8. 

Olive, M. F., H. N. Koenig, M. A. Nannini and  C. W. Hodge. "Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake." Pharmacol Biochem Behav 72(1-2): 213-20.

Olive, M. F., M. A. Nannini, C. J. Ou, H. N. Koenig and  C. W. Hodge. "Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release." Eur J Pharmacol 437(1-2): 55-61. 

Peterson, A. S. "Pixelating the brain." Genome Res 12(2): 217-8.

Rodan, A. R., J. A. Kiger, Jr. and  U. Heberlein. "Functional dissection of neuroanatomical loci regulating ethanol sensitivity in Drosophila." J Neurosci 22(21): 9490-501. 

Ryabinin, A. E., R. K. Bachtell, S. C. Heinrichs, S. Lee, C. Rivier, M. F. Olive and K. K. Mehmert. "The CRF/urocotrin system and alcohol." Alcoholism:   Clinical and Experimental Research 26: 714-722.

Whistler, J. L., B. O. Gerber, E. C. Meng, T. J. Baranski, M. von Zastrow and H. R. Bourne. "Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor." Traffic 3(12): 866-77. 

Whistler, J. L., J. Enquist, A. Marley, J. Fong, F. Gladher, P. Tsuruda, S. R. Murray and M. Von Zastrow. "Modulation of postendocytic sorting of G protein-coupled receptors." Science 297(5581): 615-20.

Wolf, F. W., A. R. Rodan, L. T. Tsai and  U. Heberlein. "High-resolution analysis of ethanol-induced locomotor stimulation in Drosophila." J Neurosci 22(24): 11035-44. 

Yaka, R., C. Thornton, A. J. Vagts, K. Phamluong,  A. Bonci and  D. Ron. "NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1." Proc Natl Acad Sci U S A 99(8): 5710-5.

Yao, L., M. P. Arolfo, D. P. Dohrman, Z. Jiang, P. Fan, S. Fuchs,  P. H. Janak,  A. S. Gordon and  I. Diamond. "betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption." Cell 109(6): 733-43. 

Zhang, L., L. Wang, A. Ravindranathan and  M. F. Miles. "A new algorithm for analysis of oligonucleotide arrays: application to expression profiling in mouse brain regions." J Mol Biol 317(2): 225-35.