Mission Statement
The Ernest Gallo Clinic and Research Center (Gallo Center) is one of world’s preeminent academic centers for the study of the biological basis of alcohol and substance abuse. Gallo Center research has a remarkable track record of innovative and important discoveries of molecular, cellular and neuronal mechanisms that underlie alcoholism and substance abuse and their co-morbidities. Gallo Center discoveries of potential molecular targets for the development of therapeutic medications are extended through preclinical and proof-of-concept clinical studies. Gallo Center technologies are further developed through intellectual property licensing and joint development relationships with biotech and pharmaceutical companies. |
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Recent News Morphine dependency blocked by single genetic change
Morphine’s serious side effect as a pain killer – its potential to create dependency – has been almost completely eliminated in research with mice by genetically modifying a single trait on the surface of neurons. The study scientists think a drug can be developed to similarly block dependency. Story>
Brain imaging and genetic studies link thinking patterns to addiction Scientists have for the first time identified brain sites that fire up more when people make impulsive decisions. In a study comparing brain activity of sober alcoholics and non-addicted people making financial decisions, the group of sober alcoholics showed significantly more "impulsive" neural activity. Story>
Drug to curb smoking also cuts alcohol dependence A drug already approved for nicotine addiction also curbs alcohol depe ndence, a new animal study shows. One dose alone cut drinking in half. The finding is particularly encouraging, the researchers say, because the animals did not turn to drinking in excess after the drug was stopped, a common pattern when people take current drugs to curb alcohol consumption. Story>
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